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ycbE [2020-04-06 18:26:05]
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ycbE [2020-04-06 18:26:05]

galactarate/glucarate transporter in (proton symport)
locus
BSU_02480
pI
9.21
mw
49.09 kDa
protein length
455 aa Sequence Blast
gene length
1368 bp Sequence Blast
function
glucarate uptake
product
galactarate/glucarate transporter in (proton symport)
essential
no
synonyms
gudP
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.3|Carbohydrate transporter]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.14|Utilization of glucarate/galactarate]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    270,396 271,763

    The protein

    Protein family

  • [SW|major facilitator superfamily] (according to UniProt)
  • Phthalate permease family (with [protein|6D08E897DD697523FD0720704A25AD4472075B6C|ExuT] and [protein|41AB19B291C766E55CA1C5BAEF157FD26B5D4297|YybO], according to UniProt)

    • [SW|Localization]

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|3542BC20C11985B3CFAA4F930E8D794700ADFD2E|ycbC]-[gene|5B66ADB81AB141982F187B1C5E3A9346AA064DE2|ycbD]-[gene|9C4932DA4DEF99263E57871A99684E3DAD93E1EC|ycbE]-[gene|372F2A420309DB0193AEF36A740EBA26410F97F2|ycbF]-[gene|1A65880F68898002EE8774F34EDC47F0243B7273|ycbG]-[gene|BA556E144975921DFDD598B0A7480C65176F0F14|ycbH]-[gene|349C99C258331962455100E2662DA2272E946C8A|ycbJ]
    description
    [Pubmed|12044674]

    regulatory mechanism

  • [protein|1A65880F68898002EE8774F34EDC47F0243B7273|YcbG]: repression, [Pubmed|12044674], in [regulon|1A65880F68898002EE8774F34EDC47F0243B7273|YcbG regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|18840696], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • induced by D-glucarate/galactarate ([protein|search|YcbG]) [Pubmed|12044674]
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    Biological materials

    Mutant

  • MGNA-C028 (ycbE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2026 NBRP B. subtilis, Japan]
  • BKE02480 ([gene|9C4932DA4DEF99263E57871A99684E3DAD93E1EC|ycbE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTATCTTCTCCTTTTC, downstream forward: _UP4_TAATATTTATGAAAGCGCTT
  • BKK02480 ([gene|9C4932DA4DEF99263E57871A99684E3DAD93E1EC|ycbE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTATCTTCTCCTTTTC, downstream forward: _UP4_TAATATTTATGAAAGCGCTT

    • References

  • 12044674